• Rat ACAT1 (Acetyl Coenzyme A Acetyltransferase 1) Sandwich ELISA Kit Ready-To-Use (STJE0013212)

Rat ACAT1 (Acetyl Coenzyme A Acetyltransferase 1) Sandwich ELISA Kit Ready-To-Use (STJE0013212)

SKU:
STJE0013212

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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 12.5pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description: This ACAT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Acat1
Gene ID: 25014
Uniprot ID: THIL_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications Succinylation at Lys-265, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5.
Function This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism.
Protein Name Acetyl-Coa Acetyltransferase - Mitochondrial
Acetoacetyl-Coa Thiolase
Database Links Reactome: R-RNO-70895
Reactome: -RNO-77108
Reactome: -RNO-77111
Cellular Localisation Mitochondrion
Alternative ELISA Names Acetyl-Coa Acetyltransferase - Mitochondrial ELISA kit
Acetoacetyl-Coa Thiolase ELISA kit
Acat1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance