FPR1 Blocking Peptide for STJ501083 peptide (STJ505336)

SKU:
STJ505336-250
$380.03
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : FPR1 Blocking Peptide for STJ501083 is synthetically produced from the 150-200 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: FPR1
Gene ID: 2357
Uniprot ID: FPR1_HUMAN
Immunogen Region: 150-200
Specificity: This blocking peptide is recommended for use in combination with FPR1 antibody, STJ501083
Immunogen: Synthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.
Tissue Specificity Neutrophils.
Post Translational Modifications Phosphorylated.which is necessary for desensitization.
Function High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Peptide Name Fmet-Leu-Phe Receptor
Fmlp Receptor
N-Formyl Peptide Receptor
Fpr
N-Formylpeptide Chemoattractant Receptor
Database Links Reactome: R-HSA-418594
Reactome: R-HSA-444473
Reactome: R-HSA-6783783
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Internalizes In Presence Of Its Ligands
Fmlp
Tafa4 And Ctsg
Alternative Peptide Names Fmet-Leu-Phe Receptor protein
Fmlp Receptor protein
N-Formyl Peptide Receptor protein
Fpr protein
N-Formylpeptide Chemoattractant Receptor protein
FPR1 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ501083 Anti-FPR1 antibody (150-200) {Biotin} (STJ501083) Rabbit Polyclonal Human/Monkey/Mouse/Rat ELISA/IHC/IP/WB
STJ505337 FPR1 Positive Control for STJ501084 peptide (STJ505337) WB
STJ504998 Thickveins Peptide Blocking Peptide peptide (STJ504998) Immunodepletion/Immunocompetition
STJ505378 hCG beta Peptide Blocking Peptide peptide (STJ505378) Immunodepletion/Immunocompetition
STJ505377 hCG beta Peptide Blocking Peptide peptide (STJ505377) Immunodepletion/Immunocompetition
!