| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
CGRP Positive Control for STJ506114 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500-1:5, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Calca |
| Gene ID: |
12310 |
| Uniprot ID: |
CALCA_MOUSE |
| Specificity: |
This is positive control is recommended for use in combination with CGRP antibody STJ506114. |
| Tissue Specificity | Detected in nerve cells of cerebrum, hippocampus and pons/midbrain in newborns, and only in nerve cells of pons/midbrain in adult. |
| Function | CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP. |
| Peptide Name | Calcitonin Gene-Related Peptide 1Alpha-Type CgrpCalcitonin Gene-Related Peptide ICgrp-I |
| Database Links | Reactome: R-MMU-418555Reactome: -MMU-419812 |
| Cellular Localisation | Secreted |
| Alternative Peptide Names | Calcitonin Gene-Related Peptide 1 proteinAlpha-Type Cgrp proteinCalcitonin Gene-Related Peptide I proteinCgrp-I proteinCalca proteinCalc protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
