Posted by M.Popov on 12th Nov 2020
Trial size CREB1 antibodies available in the Antibody Validation Project
Trial size CREB1 antibodies available in the Antibody Validation Project
Introduction:
CAMP responsive element binding protein 1 is synthesised by the CREB1 gene which helps with transcription activation, adipose cell differentiation and circadian rhythm synchronisation. Apart from its key functions in the human body, mutations of this gene lead to melanoma of soft tissues, several types of respiratory diseases and Coffin-Lowry syndrome. Furthermore, it can be used as a prognostic marker in favourable liver cancer. We provide a number of trial sized antibodies, which are suitable for CREB1 research purposes, and to help you make the right decision and find the best suited antibody for you, please find the answers to some of the key topics regarding CREB1 that we have provided in the links below.
- What is CREB1?
- Where is CREB1 found?
- What role does CREB1 play in disease?
- CREB1 antibodies in the Antibody Validation project
- Customer reviewed CREB1 antibodies
- Other CREB1 antibodies available in the Antibody Validation Project
- Popular CREB1 antibodies not currently in the Antibody Validation Project
- How does the Antibody Validation Project work?
What is CREB1?
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome, and is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Furthermore, this protein is involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Where is CREB1 found?
CREB1 is mostly found in the nucleoplasm and on tissue level, it is evenly expressed throughout the majority of the tissues and has low brain region and immune cell specificity.
What role does CREB1 play in disease?
A CREB1 mutation has been found in a patient with multiple congenital anomalies consisting of agenesis of the corpus callosum, cerebellar hypoplasia, severe neonatal respiratory distress refractory to surfactant, thymus hypoplasia, and thyroid follicular hypoplasia.
CREB1 antibodies in the Antibody Validation project
St John's Laboratory offers a variety of trial size primary antibodies which target CREB1 , which are available to try through the Antibody Validation Project. Below we highlight those which have already been reviewed, as well as others which are available to try.
Customer reviewed CREB1 antibodies
| Model | Name | Host | Clonality | Rating | Application Tested |
|---|---|---|---|---|---|
| STJ92463 | CREB-1 antibody | Rabbit | Polyclonal | 5 | |
| STJ90463 | Anti-Phospho-CREB-1 (S121) antibody | Rabbit | Polyclonal | 4 | IF |
Other CREB1 antibodies available in the Antibody Validation Project
| Model | Name | Host | Clonality | Recommended Applications |
|---|---|---|---|---|
| STJ90234 | Anti-Phospho-CREB-1 (S129) antibody | Rabbit | Polyclonal | IHC,IF,ELISA |
| STJ90235 | Anti-Phospho-CREB-1 (S133) antibody | Rabbit | Polyclonal | WB,IHC,IP,ELISA |
| STJ90565 | Anti-Phospho-CREB-1 (T100) antibody | Rabbit | Polyclonal | WB,ELISA |
| STJ92462 | Anti-CREB-1 antibody | Rabbit | Polyclonal | WB,IHC,ELISA |
| STJ92464 | Anti-CREB-1 antibody | Rabbit | Polyclonal | WB,IHC,IF,ELISA |
| STJ92465 | Anti-CREB-1 antibody | Rabbit | Polyclonal | WB,IHC,ELISA |
| STJ92466 | Anti-CREB-1 antibody | Rabbit | Polyclonal | WB,IHC,ELISA |
| STJ97114 | Anti-CREB antibody | Rabbit | Polyclonal | WB |
| STJ97445 | Anti-CREB-1 antibody | Mouse | Monoclonal | WB,IHC |
| STJ97965 | Anti-CREB-1 antibody | Mouse | Monoclonal | WB,IHC,IF,ELISA |
Popular CREB1 antibodies not currently in the Antibody Validation Project
| Model | Name | Host | Clonality | Recommended Applications |
|---|---|---|---|---|
| STJ110885 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB,IHC,IF,IP,FC |
| STJ112722 | Anti-CREB1 Antibody | Rabbit | Monoclonal | WB,IHC,IF,IP |
| STJ112927 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB,IF |
| STJ113697 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB |
| STJ113894 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB,IHC |
| STJ114197 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB |
| STJ116179 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB,IHC |
| STJ22076 | Anti-Phospho-CREB1-(S133) Antibody | Rabbit | Polyclonal | WB,IF |
| STJ22078 | Anti-Phospho-CREB1-(S129) Antibody | Rabbit | Polyclonal | WB |
| STJ22079 | Anti-Phospho-CREB1-(S133) Antibody | Rabbit | Polyclonal | WB,IHC |
| STJ22080 | Anti-Phospho-CREB1-(S142) Antibody | Rabbit | Polyclonal | WB,IHC |
| STJ23219 | Anti-CREB1 Antibody | Rabbit | Polyclonal | WB,IHC,IP |
| STJ73024 | Anti-CREB1 Antibody | Goat | Polyclonal | ELISA,WB |
How does the Antibody Validation Project work?
In order to help our customers with their choice of antibody with low risk, we offer one of the largest ranges of primary antibodies with trial size options available.
The Antibody Validation Project works like this.
1. Order your trial size antibody online.
2. Explore its suitability.
3. Return your results by posting them on the product page.
4. Receive a sample refund.
Find out more here.