Trial size BECN1 antibodies available in the Antibody Validation Project

Posted by M.Popov on 12th Nov 2020

Trial size BECN1 antibodies available in the Antibody Validation Project

Trial size BECN1 antibodies available in the Antibody Validation Project

Introduction:

BECN1 gene carries the needed information for synthesising a protein regulating autophagy and mediating vesicle-trafficking processes. Although it plays an important role in our organisms, several serious conditions have been related with a mutation or overexpression of this protein. We provide a number of trial sized antibodies, which are suitable for BECN1 research purposes, and to help you make the right decision and find the best suited antibody for you, please find the answers to some of the key topics regarding BECN1 that we have provided in the links below.

What is BECN1?

The BECN1 gene encodes a protein regulating autophagy, a catabolic process of degradation induced by starvation and also is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis.

Where is BECN1 found?

On intracellular level, this protein is found mainly in the endoplasmic reticulum, the endosome and cytosol. Smaller amounts are present in all other cell structures. It is expressed in all tissues, and has low human brain regional specificity.

What role does BECN1 play in disease?

Mutations of BECN1 lead to several cancers, cystinosis and Machado-Joseph disease: an inherited form of ataxia, worsened by the overexpression of the mutated protein.

BECN1 antibodies in the Antibody Validation project

St John's Laboratory offers a variety of trial size primary antibodies which target BECN1, which are available to try through the Antibody Validation Project. Below we highlight those which have already been reviewed, as well as others which are available to try.

Customer reviewed BECN1 antibodies

ModelNameHostClonalityRatingApplication Tested
STJ97761Anti-Beclin-1 antibody MouseMonoclonal5WB

Other BECN1 antibodies available in the Antibody Validation Project

ModelNameHostClonalityRecommended Applications
STJ97380Anti-Beclin-1 antibodyRabbitPolyclonalWB
STJ97474Anti-Beclin-1 antibodyRabbitPolyclonalWB
STJ97761Anti-Beclin-1 antibodyMouseMonoclonalWB,IHC
STJ97769Anti-Beclin-1 antibodyMouseMonoclonalIHC
STJ97770Anti-Beclin-1 antibodyMouseMonoclonalIHC
STJ97862Anti-Beclin-1 antibodyMouseMonoclonalWB,IHC,FC,ELISA
STJ98472Anti-Beclin-1 antibodyMouseMonoclonalWB
STJ99148Anti-Beclin 1 antibodyMouseMonoclonalWB,ELISA
ModelNameHostClonalityRecommended Applications
STJ112140Anti-BECN1 AntibodyMouseMonoclonalWB
STJ113348Anti-BECN1 AntibodyRabbitPolyclonalWB
STJ120021Anti-Phospho-Beclin1 (Ser234) antibody (KLH)RabbitPolyclonalWB
STJ120274Anti-Phospho-Beclin1 (Ser310) antibodyRabbitPolyclonalWB
STJ29492Anti-BECN1 AntibodyRabbitPolyclonalWB,IF

How does the Antibody Validation Project work?

In order to help our customers with their choice of antibody with low risk, we offer one of the largest ranges of primary antibodies with trial size options available.

The Antibody Validation Project works like this.
1. Order your trial size antibody online.
2. Explore its suitability.
3. Return your results by posting them on the product page.
4. Receive a sample refund.

Find out more here.