Western blot analysis of various lysates using ZFPM2 Rabbit pAb (STJ111910) at 1:1000 dilution. <br/>Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. <br/>Lysates/proteins: 25 Mu g per lane. <br/>Blocking buffer: 3% nonfat dry milk in TBST. <br/>Detection: ECL Basic Kit <br/>Exposure time: 40s.

Anti-ZFPM2 antibody (982-1151) (STJ111910)

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STJ111910
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZFPM2
Gene ID: 23414
Uniprot ID: FOG2_HUMAN
Immunogen Region: 982-1151
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 982-1151 of human ZFPM2 (NP_036214.2).
Immunogen Sequence: SPYYGIKPSDYISGSLVIHN TDIEQSRNAENESPKGQASS NGCAALKKDSLPLLPKNRGM VIVNGGLKQDERPAANPQQE NISQNPQHEDDHKSPSWISE NPLAANENVSPGIPSAEEQL SSIAKGVNGSSQAPTSGKYC RLCDIQFNNLSNFITHKKFY CSSHAAEHVK
Tissue Specificity Widely expressed at low level.
Post Translational Modifications Sumoylation reduces transcriptional repression activity.
Function Transcription regulator that plays a central role in heart morphogenesis and development of coronary vessels from epicardium, by regulating genes that are essential during cardiogenesis. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA4, GATA5 and GATA6. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. Also required in gonadal differentiation, possibly be regulating expression of SRY. Probably acts a corepressor of NR2F2.
Protein Name Zinc Finger Protein Zfpm2
Friend Of Gata Protein 2
Fog-2
Friend Of Gata 2
Hfog-2
Zinc Finger Protein 89b
Zinc Finger Protein Multitype 2
Database Links Reactome: R-HSA-9690406
Reactome: R-HSA-983231
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Zinc Finger Protein Zfpm2 antibody
Anti-Friend Of Gata Protein 2 antibody
Anti-Fog-2 antibody
Anti-Friend Of Gata 2 antibody
Anti-Hfog-2 antibody
Anti-Zinc Finger Protein 89b antibody
Anti-Zinc Finger Protein Multitype 2 antibody
Anti-ZFPM2 antibody
Anti-FOG2 antibody
Anti-ZNF89B antibody

Information sourced from Uniprot.org

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