| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Palmitoyltransferase ZDHHC17 is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZDHHC17 |
| Gene ID: |
23390 |
| Uniprot ID: |
ZDH17_HUMAN |
| Specificity: |
ZDH17 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Autopalmitoylated. Autopalmitoylation has a regulatory role in ZDHHC17-mediated Mg(2+) transport. |
| Function | Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA. Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HTT. Also palmitoylates neuronal protein GPM6A as well as SPRED1 and SPRED3. Could also play a role in axonogenesis through the regulation of NTRK1 and the downstream ERK1/ERK2 signaling cascade. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May play a role in Mg(2+) transport. Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane. Palmitoylates CASP6, thereby preventing its dimerization and subsequent activation. |
| Protein Name | Palmitoyltransferase Zdhhc17Acyltransferase Zdhhc17Dhhc Domain-Containing Cysteine-Rich Protein 17Dhhc17Huntingtin Yeast Partner HHuntingtin-Interacting Protein 14Hip-14Huntingtin-Interacting Protein 3Hip-3Huntingtin-Interacting Protein HPutative Mapk-Activating Protein Pm11Putative Nf-Kappa-B-Activating Protein 205Zinc Finger Dhhc Domain-Containing Protein 17 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembranePresynaptic Cell MembraneLow Extracellular Mg(2+) Induces Increase In Golgi And In Post-Golgi Membrane Vesicles |
| Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc17 antibodyAnti-Acyltransferase Zdhhc17 antibodyAnti-Dhhc Domain-Containing Cysteine-Rich Protein 17 antibodyAnti-Dhhc17 antibodyAnti-Huntingtin Yeast Partner H antibodyAnti-Huntingtin-Interacting Protein 14 antibodyAnti-Hip-14 antibodyAnti-Huntingtin-Interacting Protein 3 antibodyAnti-Hip-3 antibodyAnti-Huntingtin-Interacting Protein H antibodyAnti-Putative Mapk-Activating Protein Pm11 antibodyAnti-Putative Nf-Kappa-B-Activating Protein 205 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 17 antibodyAnti-ZDHHC17 antibodyAnti-HIP14 antibodyAnti-HIP3 antibodyAnti-HYPH antibodyAnti-KIAA0946 antibodyAnti-HSPC294 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
