Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ZDHHC16 (207-296) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ZDHHC16 |
Gene ID: |
84287 |
Uniprot ID: |
ZDH16_HUMAN |
Immunogen Region: |
207-296 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 207-296 of human ZDHHC16 (NP_932162.1). |
Immunogen Sequence: |
HAVLISRGETSIERHINKKE RRRLQAKGRVFRNPYNYGCL DNWKVFLGVDTGRHWLTRVL LPSSHLPHGNGMSWEPPPWV TAHSASVMAV |
Tissue Specificity | Widely expressed. |
Function | Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6. Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization. Also required for eye development. Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function. May play a role in DNA damage response. May be involved in apoptosis regulation. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway. |
Protein Name | Palmitoyltransferase Zdhhc16Abl-Philin 2Zinc Finger Dhhc Domain-Containing Protein 16Dhhc-16 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Palmitoyltransferase Zdhhc16 antibodyAnti-Abl-Philin 2 antibodyAnti-Zinc Finger Dhhc Domain-Containing Protein 16 antibodyAnti-Dhhc-16 antibodyAnti-ZDHHC16 antibodyAnti-APH2 antibodyAnti-UNQ2570 antibodyAnti-PRO6258 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance