Anti-ZDHHC16 antibody (207-296) (STJ29306)

SKU:
STJ29306

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ZDHHC16 (207-296) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ZDHHC16
Gene ID: 84287
Uniprot ID: ZDH16_HUMAN
Immunogen Region: 207-296
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 207-296 of human ZDHHC16 (NP_932162.1).
Immunogen Sequence: HAVLISRGETSIERHINKKE RRRLQAKGRVFRNPYNYGCL DNWKVFLGVDTGRHWLTRVL LPSSHLPHGNGMSWEPPPWV TAHSASVMAV
Tissue Specificity Widely expressed.
Function Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6. Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization. Also required for eye development. Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function. May play a role in DNA damage response. May be involved in apoptosis regulation. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway.
Protein Name Palmitoyltransferase Zdhhc16
Abl-Philin 2
Zinc Finger Dhhc Domain-Containing Protein 16
Dhhc-16
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Palmitoyltransferase Zdhhc16 antibody
Anti-Abl-Philin 2 antibody
Anti-Zinc Finger Dhhc Domain-Containing Protein 16 antibody
Anti-Dhhc-16 antibody
Anti-ZDHHC16 antibody
Anti-APH2 antibody
Anti-UNQ2570 antibody
Anti-PRO6258 antibody

Information sourced from Uniprot.org

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