| Function | The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis.may promote docking of RAB8A- and ARL13B-containing vesicles. |
| Protein Name | Wd Repeat-Containing Protein Wrap73Wd Repeat-Containing Protein 8Wd Repeat-Containing Protein Antisense To Tp73 Gene |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleCentriolar SatelliteEnriched In The Proximal End Of The Mother CentrioleDuring Ciliogenesis Also Associated With The Basal Body Of The Adjacent Centriole |
| Alternative Antibody Names | Anti-Wd Repeat-Containing Protein Wrap73 antibodyAnti-Wd Repeat-Containing Protein 8 antibodyAnti-Wd Repeat-Containing Protein Antisense To Tp73 Gene antibodyAnti-WRAP73 antibodyAnti-WDR8 antibody |
Information sourced from Uniprot.org
