| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-VASN (420-575) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
VASN |
| Gene ID: |
114990 |
| Uniprot ID: |
VASN_HUMAN |
| Immunogen Region: |
420-575 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 420-575 of human VASN (NP_612449.2). |
| Immunogen Sequence: |
CHLGTRHHLACLCPEGFTGL YCESQMGQGTRPSPTPVTPR PPRSLTLGIEPVSPTSLRVG LQRYLQGSSVQLRSLRLTYR NLSGPDKRLVTLRLPASLAE YTVTQLRPNATYSVCVMPLG PGRVPEGEEACGEAHTPPAV HSNHAPVTQAREGNLP |
| Tissue Specificity | Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells. |
| Post Translational Modifications | N-glycosylated. N-glycan heterogeneity at Asn-117: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major), Hex6HexNAc5 (minor) and dHex1Hex6HexNAc5 (minor). |
| Function | May act as an inhibitor of TGF-beta signaling. |
| Protein Name | VasorinProtein Slit-Like 2 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecreted |
| Alternative Antibody Names | Anti-Vasorin antibodyAnti-Protein Slit-Like 2 antibodyAnti-VASN antibodyAnti-SLITL2 antibodyAnti-UNQ314 antibodyAnti-PRO357 antibodyAnti-PRO1282 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
