| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UQCC2 (14-126) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UQCC2 |
| Gene ID: |
84300 |
| Uniprot ID: |
UQCC2_HUMAN |
| Immunogen Region: |
14-126 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 14-126 of human UQCC2 (NP_115716.1). |
| Immunogen Sequence: |
EEWPVDETKRGRDLGAYLRQ RVAQAFREGENTQVAEPEAC DQMYESLARLHSNYYKHKYP RPRDTSFSGLSLEEYKLILS TDTLEELKEIDKGMWKKLQE KFAPKGPEEDHKA |
| Tissue Specificity | Pancreas, skeletal muscle, kidney, liver and heart. |
| Function | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells. Involved in cytochrome b translation and/or stability. |
| Protein Name | Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 2Breast Cancer-Associated Protein Sga-81mMitochondrial Nucleoid Factor 1Mitochondrial Protein M19 |
| Cellular Localisation | Mitochondrion MatrixMitochondrion NucleoidMitochondrionMitochondrion Intermembrane SpaceMitochondrion Inner MembranePredominantly Expressed In The Mitochondrial Inner Membrane |
| Alternative Antibody Names | Anti-Ubiquinol-Cytochrome C Reductase Complex Assembly Factor 2 antibodyAnti-Breast Cancer-Associated Protein Sga-81m antibodyAnti-Mitochondrial Nucleoid Factor 1 antibodyAnti-Mitochondrial Protein M19 antibodyAnti-UQCC2 antibodyAnti-C6orf125 antibodyAnti-MNF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
