| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | UBAC2 |
| Gene ID: | 337867 |
| Uniprot ID: | UBAC2_HUMAN |
| Immunogen Region: | 220-310 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-310 of human UBAC2 (NP_001137544.1). |
| Immunogen Sequence: | PIFSSSEPTSEARIGMGATL DIQRQQRMELLDRQLMFSQF AQGRRQRQQQGGMINWNRLF PPLRQRQNVNYQGGRQSEPA APPLEVSEEQV |
| Function | Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. |
| Protein Name | Ubiquitin-Associated Domain-Containing Protein 2Uba Domain-Containing Protein 2Phosphoglycerate Dehydrogenase-Like Protein 1 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Ubiquitin-Associated Domain-Containing Protein 2 antibodyAnti-Uba Domain-Containing Protein 2 antibodyAnti-Phosphoglycerate Dehydrogenase-Like Protein 1 antibodyAnti-UBAC2 antibodyAnti-PHGDHL1 antibodyAnti-PSEC0110 antibody |
Information sourced from Uniprot.org