| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-UAP1 (1-290) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
UAP1 |
| Gene ID: |
6675 |
| Uniprot ID: |
UAP1_HUMAN |
| Immunogen Region: |
1-290 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human UAP1 (NP_003106.3). |
| Immunogen Sequence: |
MNINDLKLTLSKAGQEHLLR FWNELEEAQQVELYAELQAM NFEELNFFFQKAIEGFNQSS HQKNVDARMEPVPREVLGSA TRDQDQLQAWESEGLFQISQ NKVAVLLLAGGQGTRLGVAY PKGMYDVGLPSRKTLFQIQA ERILKLQQVAEKYYGNKCII PWYIMTSGRTMESTKEFFTK HKYFGLKKENVIFFQQGMLP AMSFDGKIILEEKNKVSMAP DGNGGLYRALAAQNIVEDM |
| Tissue Specificity | Widely expressed. Isoform AGX1 is more abundant in testis than isoform AGX2, while isoform AGX2 is more abundant than isoform AGX1 in somatic tissue. Expressed at low level in placenta, muscle and liver. |
| Function | Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. |
| Protein Name | Udp-N-Acetylhexosamine PyrophosphorylaseAntigen XAgxSperm-Associated Antigen 2 Includes - Udp-N-Acetylgalactosamine PyrophosphorylaseAgx-1 - Udp-N-Acetylglucosamine PyrophosphorylaseAgx-2 |
| Database Links | Reactome: R-HSA-446210 |
| Cellular Localisation | CytoplasmIn SpermatozoaLocalized To The Principal Piece Of The TailThe Neck Region Of The Head And To A Lesser ExtentThe Midpiece Of The Tail |
| Alternative Antibody Names | Anti-Udp-N-Acetylhexosamine Pyrophosphorylase antibodyAnti-Antigen X antibodyAnti-Agx antibodyAnti-Sperm-Associated Antigen 2 Includes - Udp-N-Acetylgalactosamine Pyrophosphorylase antibodyAnti-Agx-1 - Udp-N-Acetylglucosamine Pyrophosphorylase antibodyAnti-Agx-2 antibodyAnti-UAP1 antibodyAnti-SPAG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MSH6 knockout (KO) HeLa cells, using [KO Validated] MSH6 Rabbit polyclonal antibody (STJ119980) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98765/382817/STJ119980_1__09948.1713151312.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MSH6 knockout (KO) HeLa cells, using [KO Validated] MSH6 Rabbit polyclonal antibody (STJ119980) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")