| Host: |
Rabbit |
| Applications: |
WB/IP |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Tubulin Gamma-1 Chain is suitable for use in Western Blot and Immunoprecipitation research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S3948RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% thimerosal, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IP 0.5 Mu g-4 Mu g antibody for 200 Mu g-400 Mu g extracts of whole cells |
| Storage Instruction: |
Store at 4°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TUBG1 |
| Gene ID: |
7283 |
| Uniprot ID: |
TBG1_HUMAN |
| Immunogen: |
Recombinant protein of human Gamma-Tubulin. |
| Immunogen Sequence: |
MPREIITLQLGQCGNQIGFE FWKQLCAEHGISPEGIVEEF ATEGTDRKDVFFYQADDEHY IPRAVLLDLEPRVIHSILNS PYAKLYNPENIYLSEHGGGA GNNWASGFSQGEKIHEDIFD IIDREADGSDSLEGFVLCHS IAGGTGSGLGSYLLERLNDR YPKKLVQTYSVFPNQDEMSD VVVQPYNSLLTLKRLTQNAD CVVVLDNTALNRIATDRLHI QNPSFSQINQLVSTIMSAS |
| Post Translational Modifications | Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome. |
| Function | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation. |
| Protein Name | Tubulin Gamma-1 ChainGamma-1-TubulinGamma-Tubulin Complex Component 1Gcp-1 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeSpindleLocalizes To Mitotic Spindle Microtubules |
| Alternative Antibody Names | Anti-Tubulin Gamma-1 Chain antibodyAnti-Gamma-1-Tubulin antibodyAnti-Gamma-Tubulin Complex Component 1 antibodyAnti-Gcp-1 antibodyAnti-TUBG1 antibodyAnti-TUBG antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
