• Western blot analysis of extracts of various cell lines, using TRPC3 antibody (STJ110053) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-TRPC3 antibody (500-600) (STJ110053)

SKU:
STJ110053

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TRPC3 (500-600) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRPC3
Gene ID: 7222
Uniprot ID: TRPC3_HUMAN
Immunogen Region: 500-600
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TRPC3 (NP_001124170.1).
Immunogen Sequence: FRVKTTQFTWTEMLIMVWVL GMMWSECKELWLEGPREYIL QLWNVLDFGMLSIFIAAFTA RFLAFLQATKAQQYVDSYVQ ESDLSEVTLPPEIQYFTYAR D
Tissue Specificity Expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis.
Function Forms a receptor-activated non-selective calcium permeant cation channel. May be operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.
Protein Name Short Transient Receptor Potential Channel 3
Trpc3
Transient Receptor Protein 3
Trp-3
Htrp-3
Htrp3
Database Links Reactome: R-HSA-114508
Reactome: R-HSA-139853
Reactome: R-HSA-3295583
Reactome: R-HSA-418890
Reactome: R-HSA-9022699
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Short Transient Receptor Potential Channel 3 antibody
Anti-Trpc3 antibody
Anti-Transient Receptor Protein 3 antibody
Anti-Trp-3 antibody
Anti-Htrp-3 antibody
Anti-Htrp3 antibody
Anti-TRPC3 antibody
Anti-TRP3 antibody

Information sourced from Uniprot.org

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