• Western blot analysis of lysates from mouse small intestine, using TRIM2 Rabbit polyclonal antibody (STJ116605) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-TRIM2 antibody (100-300) (STJ116605)

SKU:
STJ116605

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TRIM2 (100-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRIM2
Gene ID: 23321
Uniprot ID: TRIM2_HUMAN
Immunogen Region: 100-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-300 of human TRIM2 (NP_056086.2).
Immunogen Sequence: GVAALQNNFFITNLMDVLQR TPGSNAEESSILETVTAVAA GKPLSCPNHDGNVMEFYCQS CETAMCRECTEGEHAEHPTV PLKDVVEQHKASLQVQLDAV NKRLPEIDSALQFISEIIHQ LTNQKASIVDDIHSTFDELQ KTLNVRKSVLLMELEVNYGL KHKVLQSQLDTLLQGQESIK SCSNFTAQALNHGTETEVLL V
Post Translational Modifications RING-type zinc finger-dependent and UBE2D1-dependent autoubiquitination.
Function UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity.
Protein Name Tripartite Motif-Containing Protein 2
E3 Ubiquitin-Protein Ligase Trim2
Ring Finger Protein 86
Ring-Type E3 Ubiquitin Transferase Trim2
Database Links Reactome: R-HSA-877300
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Tripartite Motif-Containing Protein 2 antibody
Anti-E3 Ubiquitin-Protein Ligase Trim2 antibody
Anti-Ring Finger Protein 86 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Trim2 antibody
Anti-TRIM2 antibody
Anti-KIAA0517 antibody
Anti-RNF86 antibody

Information sourced from Uniprot.org

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