• Western blot analysis of extracts of various cell lines, using TRAF3IP1 antibody (STJ111513) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.

Anti-TRAF3IP1 antibody (386-625) (STJ111513)

SKU:
STJ111513

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TRAF3IP1 (386-625) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TRAF3IP1
Gene ID: 26146
Uniprot ID: MIPT3_HUMAN
Immunogen Region: 386-625
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 386-625 of human TRAF3IP1 (NP_001132962.1).
Immunogen Sequence: SSNIRRIPRPGSARPAPPRV KRQDSMEALQMDRSGSGKTV SNVITESHNSDNEEDDQFVV EAAPQLSEMSEIEMVTAVEL EEEEKHGGLVKKILETKKDY EKLQQSPKPGEKERSLFESA WKKEKDIVSKEIEKLRTSIQ TLCKSALPLGKIMDYIQEDV DAMQNELQMWHSENRQHAEA LQQEQRITDCAVEPLKAELA ELEQLIKDQQDKICAVKANI LKNEEKIQKMVYSINLTSR
Tissue Specificity Ubiquitous.
Function Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis.
Protein Name Traf3-Interacting Protein 1
Interleukin-13 Receptor Alpha 1-Binding Protein 1
Intraflagellar Transport Protein 54 Homolog
Microtubule-Interacting Protein Associated With Traf3
Mip-T3
Database Links Reactome: R-HSA-5620924
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Cilium
Cilium Axoneme
Cilium Basal Body
Microtubules
In The Cilium
It Is Observed At The Ciliary Base
Ciliary Transition Zone And Ciliary Tip
Alternative Antibody Names Anti-Traf3-Interacting Protein 1 antibody
Anti-Interleukin-13 Receptor Alpha 1-Binding Protein 1 antibody
Anti-Intraflagellar Transport Protein 54 Homolog antibody
Anti-Microtubule-Interacting Protein Associated With Traf3 antibody
Anti-Mip-T3 antibody
Anti-TRAF3IP1 antibody
Anti-IFT54 antibody
Anti-MIPT3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance