Tissue Specificity | Ubiquitous. |
Function | Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis. |
Protein Name | Traf3-Interacting Protein 1Interleukin-13 Receptor Alpha 1-Binding Protein 1Intraflagellar Transport Protein 54 HomologMicrotubule-Interacting Protein Associated With Traf3Mip-T3 |
Database Links | Reactome: R-HSA-5620924 |
Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumCilium AxonemeCilium Basal BodyMicrotubulesIn The CiliumIt Is Observed At The Ciliary BaseCiliary Transition Zone And Ciliary Tip |
Alternative Antibody Names | Anti-Traf3-Interacting Protein 1 antibodyAnti-Interleukin-13 Receptor Alpha 1-Binding Protein 1 antibodyAnti-Intraflagellar Transport Protein 54 Homolog antibodyAnti-Microtubule-Interacting Protein Associated With Traf3 antibodyAnti-Mip-T3 antibodyAnti-TRAF3IP1 antibodyAnti-IFT54 antibodyAnti-MIPT3 antibody |
Information sourced from Uniprot.org