Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TOM20 (1-145) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TOMM20 |
Gene ID: |
9804 |
Uniprot ID: |
TOM20_HUMAN |
Immunogen Region: |
1-145 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human TOMM20 (NP_055580.1). |
Immunogen Sequence: |
MVGRNSAIAAGVCGALFIGY CIYFDRKRRSDPNFKNRLRE RRKKQKLAKERAGLSKLPDL KDAEAVQKFFLEEIQLGEEL LAQGEYEKGVDHLTNAIAVC GQPQQLLQVLQQTLPPPVFQ MLLTKLPTISQRIVSAQSLA EDDVE |
Post Translational Modifications | Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30. |
Function | Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases. |
Protein Name | Mitochondrial Import Receptor Subunit Tom20 HomologMitochondrial 20 Kda Outer Membrane ProteinOuter Mitochondrial Membrane Receptor Tom20 |
Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-5205685Reactome: R-HSA-5689880 |
Cellular Localisation | Mitochondrion Outer MembraneSingle-Pass Membrane Protein |
Alternative Antibody Names | Anti-Mitochondrial Import Receptor Subunit Tom20 Homolog antibodyAnti-Mitochondrial 20 Kda Outer Membrane Protein antibodyAnti-Outer Mitochondrial Membrane Receptor Tom20 antibodyAnti-TOMM20 antibodyAnti-KIAA0016 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance