| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
TNFSF15 |
| Gene ID: |
9966 |
| Uniprot ID: |
TNF15_HUMAN |
| Immunogen Region: |
72-251 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 72-251 of human TNFSF15 (NP_005109.2). |
| Immunogen Sequence: |
LKGQEFAPSHQQVYAPLRAD GDKPRAHLTVVRQTPTQHFK NQFPALHWEHELGLAFTKNR MNYTNKFLLIPESGDYFIYS QVTFRGMTSECSEIRQAGRP NKPDSITVVITKVTDSYPEP TQLLMGTKSVCEVGSNWFQP IYLGAMFSLQEGDKLMVNVS DISLVDYTKEDKTFFGAFLL |
| Tissue Specificity | Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. |
| Function | Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 15Tnf Ligand-Related Molecule 1Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane ProteinTumor Necrosis Factor Ligand Superfamily Member 15Secreted Form: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Ligand Superfamily Member 15 antibodyAnti-Tnf Ligand-Related Molecule 1 antibodyAnti-Vascular Endothelial Cell Growth Inhibitor Cleaved Into - Tumor Necrosis Factor Ligand Superfamily Member 15 - Membrane Form - Tumor Necrosis Factor Ligand Superfamily Member 15 - Secreted Form antibodyAnti-TNFSF15 antibodyAnti-TL1 antibodyAnti-VEGI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
