| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TINAGL1 |
| Gene ID: | 64129 |
| Uniprot ID: | TINAL_HUMAN |
| Immunogen Region: | 258-467 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 258-467 of human TINAGL1 (NP_071447.1). |
| Immunogen Sequence: | NLLSCDTHQQQGCRGGRLDG AWWFLRRRGVVSDHCYPFSG RERDEAGPAPPCMMHSRAMG RGKRQATAHCPNSYVNNNDI YQVTPVYRLGSNDKEIMKEL MENGPVQALMEVHEDFFLYK GGIYSHTPVSLGRPERYRRH GTHSVKITGWGEETLPDGRT LKYWTAANSWGPAWGERGHF RIVRGVNECDIESFVLGVWG RVGMEDMGHH |
| Tissue Specificity | Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary, spleen, testis and prostate. Predominantly found in vascular smooth muscle cells, but also in cardiac and skeletal muscle cells as well as kidney. |
| Post Translational Modifications | Glycosylated. |
| Function | May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein. |
| Protein Name | Tubulointerstitial Nephritis Antigen-Like Glucocorticoid-Inducible Protein 5 Oxidized Ldl-Responsive Gene 2 Protein Olrg-2 Tubulointerstitial Nephritis Antigen-Related Protein Tin Ag-Related Protein Tin-Ag-Rp |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Tubulointerstitial Nephritis Antigen-Like antibody Anti-Glucocorticoid-Inducible Protein 5 antibody Anti-Oxidized Ldl-Responsive Gene 2 Protein antibody Anti-Olrg-2 antibody Anti-Tubulointerstitial Nephritis Antigen-Related Protein antibody Anti-Tin Ag-Related Protein antibody Anti-Tin-Ag-Rp antibody Anti-TINAGL1 antibody Anti-GIS5 antibody Anti-LCN7 antibody Anti-OLRG2 antibody Anti-TINAGL antibody Anti-PP6614 antibody Anti-PSEC0088 antibody Anti-UNQ204 antibody Anti-PRO230 antibody |
Information sourced from Uniprot.org