| Host: | Mouse |
| Applications: | ELISA/IF/IP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Short Description : | Mouse monoclonal antibody anti-F-Box-Like/Wd Repeat-Containing Protein Tbl1x is suitable for use in ELISA, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SAA0233 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | 0.01M PBS |
| Purification: | Protein A/G purified from cell culture supernatant |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Gene Symbol: | TBL1X |
| Gene ID: | 6907 |
| Uniprot ID: | TBL1X_HUMAN |
| Function | F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. |
| Protein Name | F-Box-Like/Wd Repeat-Containing Protein Tbl1xSmap55Transducin Beta-Like Protein 1xTransducin-Beta-Like Protein 1 - X-Linked |
| Database Links | Reactome: R-HSA-1368082Reactome: R-HSA-1368108Reactome: R-HSA-1989781Reactome: R-HSA-2122947Reactome: R-HSA-2151201Reactome: R-HSA-2426168Reactome: R-HSA-2644606Reactome: R-HSA-2894862Reactome: R-HSA-3214815Reactome: R-HSA-350054Reactome: R-HSA-381340Reactome: R-HSA-400206Reactome: R-HSA-400253Reactome: R-HSA-9022537Reactome: R-HSA-9022692Reactome: R-HSA-9029569Reactome: R-HSA-9609690Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | NucleusColocalized With Mecp2 To The Heterochromatin Foci |
| Alternative Antibody Names | Anti-F-Box-Like/Wd Repeat-Containing Protein Tbl1x antibodyAnti-Smap55 antibodyAnti-Transducin Beta-Like Protein 1x antibodyAnti-Transducin-Beta-Like Protein 1 - X-Linked antibodyAnti-TBL1X antibodyAnti-TBL1 antibody |
Information sourced from Uniprot.org