| Post Translational Modifications | The Thr-60 variant is predicted to introduce a novel N-linked glycosylation site at Asn-58. The addition of even a short carbohydrate group at Asn-58 is predicted to disrupt one of the contact surfaces required for stability of a dimer. Therefore a Thr-60 variant N-glycosylated at Asn-58 is predicted to be precluded from forming homodimers or heterodimers. |
| Function | Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. |
| Protein Name | Taste Receptor Type 1 Member 3Saccharin Preference ProteinSweet Taste Receptor T1r3 |
| Database Links | Reactome: R-MMU-418594Reactome: -MMU-420499Reactome: -MMU-9717207 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Taste Receptor Type 1 Member 3 antibodyAnti-Saccharin Preference Protein antibodyAnti-Sweet Taste Receptor T1r3 antibodyAnti-Tas1r3 antibodyAnti-Sac antibodyAnti-T1r3 antibodyAnti-Tr3 antibody |
Information sourced from Uniprot.org
