| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TACR1 (308-407) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TACR1 |
| Gene ID: |
6869 |
| Uniprot ID: |
NK1R_HUMAN |
| Immunogen Region: |
308-407 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 308-407 of human Neurokinin 1 Receptor (NK1R) (NP_001049.1). |
| Immunogen Sequence: |
LNDRFRLGFKHAFRCCPFIS AGDYEGLEMKSTRYLQTQGS VYKVSRLETTISTVVGAHEE EPEDGPKATPSSLDLTSNCS SRSDSKTMTESFSFSSNVLS |
| Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
| Protein Name | Substance-P ReceptorSprNk-1 ReceptorNk-1rTachykinin Receptor 1 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Substance-P Receptor antibodyAnti-Spr antibodyAnti-Nk-1 Receptor antibodyAnti-Nk-1r antibodyAnti-Tachykinin Receptor 1 antibodyAnti-TACR1 antibodyAnti-NK1R antibodyAnti-TAC1R antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
