| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-STOM (55-288) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
STOM |
| Gene ID: |
2040 |
| Uniprot ID: |
STOM_HUMAN |
| Immunogen Region: |
55-288 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 55-288 of human STOM (NP_004090.4). |
| Immunogen Sequence: |
KIIKEYERAIIFRLGRILQG GAKGPGLFFILPCTDSFIKV DMRTISFDIPPQEILTKDSV TISVDGVVYYRVQNATLAVA NITNADSATRLLAQTTLRNV LGTKNLSQILSDREEIAHNM QSTLDDATDAWGIKVERVEI KDVKLPVQLQRAMAAEAEAS REARAKVIAAEGEMNASRAL KEASMVITESPAALQLRYLQ TLTTIAAEKNSTIVFPLPID MLQGIIGAKHSHLG |
| Tissue Specificity | Detected in erythrocytes (at protein level). Widely expressed. |
| Function | Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity. |
| Protein Name | StomatinErythrocyte Band 7 Integral Membrane ProteinErythrocyte Membrane Protein Band 7.2Protein 7.2b |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-9013026Reactome: R-HSA-9013106Reactome: R-HSA-9013148Reactome: R-HSA-9013406Reactome: R-HSA-9013407Reactome: R-HSA-9013409 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonLipid-AnchorMembrane RaftMelanosomeCytoplasmic VesicleLocalizes To Juxtanuclear Structure Probably Derived From The Golgi ApparatusColocalizes With Cortical Actin Microfilaments At Small Plasma Membrane ProtrusionsAssociates With Alpha-Granular Lipid RaftsTranslocates From The Alpha-Granular Lipid Rafts To The Cell Membrane On Thrombin Activation And Selectively Enriched In Released MicrovesiclesIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Stomatin antibodyAnti-Erythrocyte Band 7 Integral Membrane Protein antibodyAnti-Erythrocyte Membrane Protein Band 7.2 antibodyAnti-Protein 7.2b antibodyAnti-STOM antibodyAnti-BND7 antibodyAnti-EPB72 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
