| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ST14 (566-855) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ST14 |
| Gene ID: |
6768 |
| Uniprot ID: |
ST14_HUMAN |
| Immunogen Region: |
566-855 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1). |
| Immunogen Sequence: |
TCTKHTYRCLNGLCLSKGNP ECDGKEDCSDGSDEKDCDCG LRSFTRQARVVGGTDADEGE WPWQVSLHALGQGHICGASL ISPNWLVSAAHCYIDDRGFR YSDPTQWTAFLGLHDQSQRS APGVQERRLKRIISHPFFND FTFDYDIALLELEKPAEYSS MVRPICLPDASHVFPAGKAI WVTGWGHTQYGGTGALILQK GEIRVINQTTCENLLPQQIT PRMMCVGFLSGGVDSCQGD |
| Function | Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. Proteolytically cleaves and therefore activates TMPRSS13. |
| Protein Name | Suppressor Of Tumorigenicity 14 ProteinMatriptaseMembrane-Type Serine Protease 1Mt-Sp1ProstaminSerine Protease 14Serine Protease Tadg-15Tumor-Associated Differentially-Expressed Gene 15 Protein |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Suppressor Of Tumorigenicity 14 Protein antibodyAnti-Matriptase antibodyAnti-Membrane-Type Serine Protease 1 antibodyAnti-Mt-Sp1 antibodyAnti-Prostamin antibodyAnti-Serine Protease 14 antibodyAnti-Serine Protease Tadg-15 antibodyAnti-Tumor-Associated Differentially-Expressed Gene 15 Protein antibodyAnti-ST14 antibodyAnti-PRSS14 antibodyAnti-SNC19 antibodyAnti-TADG15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
