| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SSTR5 (275-364) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SSTR5 |
| Gene ID: |
6755 |
| Uniprot ID: |
SSR5_HUMAN |
| Immunogen Region: |
275-364 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 275-364 of human SSTR5 (NP_001044.1). |
| Immunogen Sequence: |
ALPQEPASAGLYFFVVILSY ANSCANPVLYGFLSDNFRQS FQKVLCLRKGSGAKDADATE PRPDRIRQQQEATPPAHRAA ANGLMQTSKL |
| Tissue Specificity | Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. |
| Post Translational Modifications | Palmitoylated by ZDHHC5, but not ZDHHC3, nor ZDHHC8. Palmitoylation creates an additional intracellular loop which is thought to be important for efficient coupling to G-proteins and may target the protein to lipid rafts. |
| Function | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization. |
| Protein Name | Somatostatin Receptor Type 5Ss-5-RSs5-RSs5rSst5 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Somatostatin Receptor Type 5 antibodyAnti-Ss-5-R antibodyAnti-Ss5-R antibodyAnti-Ss5r antibodyAnti-Sst5 antibodyAnti-SSTR5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
