| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPINT2 |
| Gene ID: | 10653 |
| Uniprot ID: | SPIT2_HUMAN |
| Immunogen Region: | 28-197 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 28-197 of human SPINT2 (NP_066925.1). |
| Immunogen Sequence: | ADRERSIHDFCLVSKVVGRC RASMPRWWYNVTDGSCQLFV YGGCDGNSNNYLTKEECLKK CATVTENATGDLATSRNAAD SSVPSAPRRQDSEDHSSDMF NYEEYCTANAVTGPCRASFP RWYFDVERNSCNNFIYGGCR GNKNSYRSEEACMLRCFRQQ ENPPLPLGSK |
| Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
| Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
| Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Antibody Names | Anti-Kunitz-Type Protease Inhibitor 2 antibodyAnti-Hepatocyte Growth Factor Activator Inhibitor Type 2 antibodyAnti-Hai-2 antibodyAnti-Placental Bikunin antibodyAnti-SPINT2 antibodyAnti-HAI2 antibodyAnti-KOP antibody |
Information sourced from Uniprot.org