Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-SNRPD2 (1-118) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | SNRPD2 |
Gene ID: | 6633 |
Uniprot ID: | SMD2_HUMAN |
Immunogen Region: | 1-118 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human SNRPD2 (NP_004588.1). |
Immunogen Sequence: | MSLLNKPKSEMTPEELQKRE EEEFNTGPLSVLTQSVKNNT QVLINCRNNKKLLGRVKAFD RHCNMVLENVKEMWTEVPKS GKGKKKSKPVNKDRYISKMF LRGDSVIVVLRNPLIAGK |
Function | Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. |
Protein Name | Small Nuclear Ribonucleoprotein Sm D2 Sm-D2 Snrnp Core Protein D2 |
Database Links | Reactome: R-HSA-191859 Reactome: R-HSA-72163 Reactome: R-HSA-72165 Reactome: R-HSA-9754678 |
Cellular Localisation | Cytoplasm Cytosol Nucleus Smn-Mediated Assembly Into Core Snrnps Occurs In The Cytosol Before Smn-Mediated Transport To The Nucleus To Be Included In Spliceosomes |
Alternative Antibody Names | Anti-Small Nuclear Ribonucleoprotein Sm D2 antibody Anti-Sm-D2 antibody Anti-Snrnp Core Protein D2 antibody Anti-SNRPD2 antibody Anti-SNRPD1 antibody |
Information sourced from Uniprot.org