| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SNAP29 (1-258) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:4000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SNAP29 |
| Gene ID: |
9342 |
| Uniprot ID: |
SNP29_HUMAN |
| Immunogen Region: |
1-258 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human SNAP29 (NP_004773.1). |
| Immunogen Sequence: |
MSAYPKSYNPFDDDGEDEGA RPAPWRDARDLPDGPDAPAD RQQYLRQEVLRRAEATAAST SRSLALMYESEKVGVASSEE LARQRGVLERTEKMVDKMDQ DLKISQKHINSIKSVFGGLV NYFKSKPVETPPEQNGTLTS QPNNRLKEAISTSKEQEAKY QASHPNLRKLDDTDPVPRGA GSAMSTDAYPKNPHLRAYHQ KIDSNLDELSMGLGRLKDIA LGMQTEIEEQDDILDRLTT |
| Tissue Specificity | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. |
| Function | SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions. |
| Protein Name | Synaptosomal-Associated Protein 29Snap-29Soluble 29 Kda Nsf Attachment ProteinVesicle-Membrane Fusion Protein Snap-29 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-6811438 |
| Cellular Localisation | CytoplasmGolgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic VesicleAutophagosome MembraneCell ProjectionCilium MembraneAppears To Be Mostly Membrane-BoundProbably Via Interaction With SyntaxinsBut A Significant Portion Is CytoplasmicLocalizes To The Ciliary Pocket From Where The Cilium Protrudes |
| Alternative Antibody Names | Anti-Synaptosomal-Associated Protein 29 antibodyAnti-Snap-29 antibodyAnti-Soluble 29 Kda Nsf Attachment Protein antibodyAnti-Vesicle-Membrane Fusion Protein Snap-29 antibodyAnti-SNAP29 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
