| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLURP1 (1-103) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLURP1 |
| Gene ID: |
57152 |
| Uniprot ID: |
SLUR1_HUMAN |
| Immunogen Region: |
1-103 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human SLURP1 (NP_065160.1). |
| Immunogen Sequence: |
MASRWAVQLLLVAAWSMGCG EALKCYTCKEPMTSASCRTI TRCKPEDTACMTTLVTVEAE YPFNQSPVVTRSCSSSCVAT DPDSIGAAHLIFCCFRDLCN SEL |
| Tissue Specificity | Granulocytes. Expressed in skin. Predominantly expressed in the granular layer of skin, notably the acrosyringium. Identified in several biological fluids such as sweat, saliva, tears, plasma and urine. |
| Function | Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation.the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca(2+) signaling. Seems to have an immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation. |
| Protein Name | Secreted Ly-6/Upar-Related Protein 1Slurp-1Ars Component BArs(Component B-81/SAnti-Neoplastic Urinary ProteinAnup |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Secreted Ly-6/Upar-Related Protein 1 antibodyAnti-Slurp-1 antibodyAnti-Ars Component B antibodyAnti-Ars(Component B-81/S antibodyAnti-Anti-Neoplastic Urinary Protein antibodyAnti-Anup antibodyAnti-SLURP1 antibodyAnti-ARS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
