| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cationic Amino Acid Transporter 2 (200-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC7A2 |
| Gene ID: |
6542 |
| Uniprot ID: |
CTR2_HUMAN |
| Immunogen Region: |
200-300 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human SLC7A2 (NP_001008539.3). |
| Immunogen Sequence: |
LVLLFVMVAGFVKGNVANWK ISEEFLKNISASAREPPSEN GTSIYGAGGFMPYGFTGTLA GAATCFYAFVGFDCIATTGE EVRNPQKAIPIGIVTSLLVC F |
| Tissue Specificity | Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart. |
| Function | Functions as permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine).the affinity for its substrates differs between isoforms created by alternative splicing. May play a role in classical or alternative activation of macrophages via its role in arginine transport. Isoform 1: Functions as permease that mediates the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). Shows a much higher affinity for L-arginine and L-homoarginine than isoform 2. Isoform 2: Functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine). |
| Protein Name | Cationic Amino Acid Transporter 2Cat-2Cat2Low Affinity Cationic Amino Acid Transporter 2Solute Carrier Family 7 Member 2 |
| Database Links | Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cationic Amino Acid Transporter 2 antibodyAnti-Cat-2 antibodyAnti-Cat2 antibodyAnti-Low Affinity Cationic Amino Acid Transporter 2 antibodyAnti-Solute Carrier Family 7 Member 2 antibodyAnti-SLC7A2 antibodyAnti-ATRC2 antibodyAnti-CAT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
