Western blot analysis of extracts of mouse kidney, using SLC6A15 antibody (STJ112468) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-SLC6A15 antibody (350-450) (STJ112468)

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STJ112468
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC6A15
Gene ID: 55117
Uniprot ID: S6A15_HUMAN
Immunogen Region: 350-450
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 350-450 of human SLC6A15 (NP_877499.1).
Immunogen Sequence: LVVFAVLGFKANVINEKCIT QNSETIMKFLKMGNISQDII PHHINLSTVTAEDYHLVYDI IQKVKEEEFPALHLNSCKIE EELNKAVQGTGLAFIAFTEA M
Tissue Specificity Almost exclusively expressed in the brain.
Function Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Can also transport low-affinity substrates such as alanine, phenylalanine, glutamine and pipecolic acid. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1:1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent.
Protein Name Sodium-Dependent Neutral Amino Acid Transporter B(0at2
Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73
Sodium-Coupled Branched-Chain Amino-Acid Transporter 1
Solute Carrier Family 6 Member 15
Transporter V7-3
Database Links Reactome: R-HSA-352230
Reactome: R-HSA-442660
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Sodium-Dependent Neutral Amino Acid Transporter B(0at2 antibody
Anti-Sodium- And Chloride-Dependent Neurotransmitter Transporter Ntt73 antibody
Anti-Sodium-Coupled Branched-Chain Amino-Acid Transporter 1 antibody
Anti-Solute Carrier Family 6 Member 15 antibody
Anti-Transporter V7-3 antibody
Anti-SLC6A15 antibody
Anti-B0AT2 antibody
Anti-NTT73 antibody
Anti-SBAT1 antibody

Information sourced from Uniprot.org

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