• Western blot analysis of extracts of various cell lines, using SLC44A2 antibody (STJ117372) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.

Anti-SLC44A2 antibody (150-250) (STJ117372)

SKU:
STJ117372

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC44A2 (150-250) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC44A2
Gene ID: 57153
Uniprot ID: CTL2_HUMAN
Immunogen Region: 150-250
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SLC44A2 (NP_065161.3).
Immunogen Sequence: AEVLQDGDCPAVLIPSKPLA RRCFPAIHAYKGVLMVGNET TYEDGHGSRKNITDLVEGAK KANGVLEARQLAMRIFEDYT VSWYWIIIGLVIAMAMSLLF I
Tissue Specificity Present in supporting cells of the inner ear (at protein level). Isoform 3: Expressed in inner ear vestibular tissue.
Function Isoform 1: Choline/H+ antiporter, mainly in mitochodria. Also acts as a low-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway. Isoform 3: Does not exhibit choline transporter activity.
Protein Name Choline Transporter-Like Protein 2
Solute Carrier Family 44 Member 2
Database Links Reactome: R-HSA-1483191
Reactome: R-HSA-425366
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Mitochondrion Outer Membrane
Mainly Expressed In Mitochondria
Alternative Antibody Names Anti-Choline Transporter-Like Protein 2 antibody
Anti-Solute Carrier Family 44 Member 2 antibody
Anti-SLC44A2 antibody
Anti-CTL2 antibody
Anti-PSEC0210 antibody

Information sourced from Uniprot.org

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