• Western blot analysis of various lysates using FATP4/SLC27A4 Rabbit polyclonal antibody (STJ118542) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-SLC27A4 antibody (574-643) (STJ118542)

SKU:
STJ118542

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC27A4 (574-643) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC27A4
Gene ID: 10999
Uniprot ID: S27A4_HUMAN
Immunogen Region: 574-643
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 574-643 of human FATP4/SLC27A4 (NP_005085.2).
Immunogen Sequence: PLYARPIFLRLLPELHKTGT YKFQKTELRKEGFDPAIVKD PLFYLDAQKGRYVPLDQEAY SRIQAGEEKL
Tissue Specificity Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in peripheral leukocytes, bone marrow, skeletal muscle and aorta. Expressed in adipose tissue. Expressed in brain gray matter.
Function Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Probably involved in fatty acid transport across the blood barrier. Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones.
Protein Name Long-Chain Fatty Acid Transport Protein 4
Fatp-4
Fatty Acid Transport Protein 4
Arachidonate--Coa Ligase
Long-Chain-Fatty-Acid--Coa Ligase
Solute Carrier Family 27 Member 4
Very Long-Chain Acyl-Coa Synthetase 4
Acsvl4
Database Links Reactome: R-HSA-5619108
Reactome: R-HSA-804914
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Long-Chain Fatty Acid Transport Protein 4 antibody
Anti-Fatp-4 antibody
Anti-Fatty Acid Transport Protein 4 antibody
Anti-Arachidonate--Coa Ligase antibody
Anti-Long-Chain-Fatty-Acid--Coa Ligase antibody
Anti-Solute Carrier Family 27 Member 4 antibody
Anti-Very Long-Chain Acyl-Coa Synthetase 4 antibody
Anti-Acsvl4 antibody
Anti-SLC27A4 antibody
Anti-ACSVL4 antibody
Anti-FATP4 antibody

Information sourced from Uniprot.org

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