| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLC25A18 |
| Gene ID: | 83733 |
| Uniprot ID: | GHC2_HUMAN |
| Immunogen Region: | 90-220 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-220 of human SLC25A18 (NP_113669.1). |
| Immunogen Sequence: | RRLLMEDGMQRNLKMEMLAG CGAGMCQVVVTCPMEMLKIQ LQDAGRLAVHHQGSASAPST SRSYTTGSASTHRRPSATLI AWELLRTQGLAGLYRGLGAT LLRDIPFSIIYFPLFANLNN LGFNELAGKAS |
| Tissue Specificity | Expressed in brain, to a lesser extent in testis, and poorly in all the other tissues. |
| Function | Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system). |
| Protein Name | Mitochondrial Glutamate Carrier 2Gc-2Glutamate/H(+ Symporter 2Solute Carrier Family 25 Member 18 |
| Database Links | Reactome: R-HSA-428643Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Glutamate Carrier 2 antibodyAnti-Gc-2 antibodyAnti-Glutamate/H(+ Symporter 2 antibodyAnti-Solute Carrier Family 25 Member 18 antibodyAnti-SLC25A18 antibodyAnti-GC2 antibody |
Information sourced from Uniprot.org