| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-SIT1 (Internal) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
SIT1 |
| Gene ID: |
27240 |
| Uniprot ID: |
SIT1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_055265.1 |
| Immunogen Sequence: |
HLSQWTRGRSRSH |
| Post Translational Modifications | Phosphorylated on tyrosines by LCK, FYN or ZAP70 upon TCR activation.which leads to the recruitment of PTPN11, GRB2 and CSK. |
| Function | Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells. |
| Protein Name | Signaling Threshold-Regulating Transmembrane Adapter 1Shp2-Interacting Transmembrane Adapter ProteinSuppression-Inducing Transmembrane Adapter 1Gp30/40 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Signaling Threshold-Regulating Transmembrane Adapter 1 antibodyAnti-Shp2-Interacting Transmembrane Adapter Protein antibodyAnti-Suppression-Inducing Transmembrane Adapter 1 antibodyAnti-Gp30/40 antibodyAnti-SIT1 antibodyAnti-SIT antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
