Function | Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin. |
Protein Name | Actin-Histidine N-MethyltransferaseProtein-L-Histidine N-Tele-MethyltransferaseSet Domain-Containing Protein 3Hsetd3 |
Database Links | Reactome: R-HSA-3214841 |
Cellular Localisation | CytoplasmNucleusLocalizes Mainly In The Cytoplasm |
Alternative Antibody Names | Anti-Actin-Histidine N-Methyltransferase antibodyAnti-Protein-L-Histidine N-Tele-Methyltransferase antibodyAnti-Set Domain-Containing Protein 3 antibodyAnti-Hsetd3 antibodyAnti-SETD3 antibodyAnti-C14orf154 antibody |
Information sourced from Uniprot.org