| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SERPINA4 (178-427) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SERPINA4 |
| Gene ID: |
5267 |
| Uniprot ID: |
KAIN_HUMAN |
| Immunogen Region: |
178-427 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 178-427 of human Kallistatin (SERPINA4) (NP_006206.2). |
| Immunogen Sequence: |
TIQLINDHVKKETRGKIVDL VSELKKDVLMVLVNYIYFKA LWEKPFISSRTTPKDFYVDE NTTVRVPMMLQDQEHHWYLH DRYLPCSVLRMDYKGDATVF FILPNQGKMREIEEVLTPEM LMRWNNLLRKRNFYKKLELH LPKFSISGSYVLDQILPRLG FTDLFSKWADLSGITKQQKL EASKSFHKATLDVDEAGTEA AAATSFAIKFFSAQTNRHIL RFNRPFLVVIFSTSTQSVL |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. |
| Protein Name | KallistatinKallikrein InhibitorPeptidase Inhibitor 4Pi-4Serpin A4 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Kallistatin antibodyAnti-Kallikrein Inhibitor antibodyAnti-Peptidase Inhibitor 4 antibodyAnti-Pi-4 antibodyAnti-Serpin A4 antibodyAnti-SERPINA4 antibodyAnti-KST antibodyAnti-PI4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
