||WB, IHC, IF, IP
||FOR RESEARCH USE ONLY (RUO).
||Rabbit monoclonal antibody anti-SARS-COV-2 N Protein is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and Immunoprecipitation.
||PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
||WB 1:1000-1:5000ELISA 1:1000-1:5000FCM 1:50-1:200IHC 1:50-1:200IF 1:50-1:200IP 1:50-1:200
||Store at 4°C. Avoid freeze/thaw cycles.
||Recombinant fusion protein of SARS-COV-2 Nucleoprotein.
| Background || Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance