Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-S100A3 (1-101) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
S100A3 |
Gene ID: |
6274 |
Uniprot ID: |
S10A3_HUMAN |
Immunogen Region: |
1-101 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A3 (NP_002951.1). |
Immunogen Sequence: |
MARPLEQAVAAIVCTFQEYA GRCGDKYKLCQAELKELLQK ELATWTPTEFRECDYNKFMS VLDTNKDCEVDFVEYVRSLA CLCLYCHEYFKDCPSEPPCS Q |
Tissue Specificity | Skin specific, specifically expressed at the inner endocuticle of hair fibers. |
Post Translational Modifications | More than half of the arginine residues undergo citrullination by PAD1 and PAD2. Arg-51 is specifically citrullinated by PAD3 and promotes tetramerization. |
Function | Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation. |
Protein Name | Protein S100-A3Protein S-100eS100 Calcium-Binding Protein A3 |
Cellular Localisation | Cytoplasm |
Alternative Antibody Names | Anti-Protein S100-A3 antibodyAnti-Protein S-100e antibodyAnti-S100 Calcium-Binding Protein A3 antibodyAnti-S100A3 antibodyAnti-S100E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance