| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | S100A3 |
| Gene ID: | 6274 |
| Uniprot ID: | S10A3_HUMAN |
| Immunogen Region: | 1-101 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-101 of human S100A3 (NP_002951.1). |
| Immunogen Sequence: | MARPLEQAVAAIVCTFQEYA GRCGDKYKLCQAELKELLQK ELATWTPTEFRECDYNKFMS VLDTNKDCEVDFVEYVRSLA CLCLYCHEYFKDCPSEPPCS Q |
| Tissue Specificity | Skin specific, specifically expressed at the inner endocuticle of hair fibers. |
| Post Translational Modifications | More than half of the arginine residues undergo citrullination by PAD1 and PAD2. Arg-51 is specifically citrullinated by PAD3 and promotes tetramerization. |
| Function | Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation. |
| Protein Name | Protein S100-A3Protein S-100eS100 Calcium-Binding Protein A3 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein S100-A3 antibodyAnti-Protein S-100e antibodyAnti-S100 Calcium-Binding Protein A3 antibodyAnti-S100A3 antibodyAnti-S100E antibody |
Information sourced from Uniprot.org