| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RNASEH2B (1-290) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RNASEH2B |
| Gene ID: |
79621 |
| Uniprot ID: |
RNH2B_HUMAN |
| Immunogen Region: |
1-290 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human RNASEH2B (NP_078846.2). |
| Immunogen Sequence: |
MAAGVDCGDGVGARQHVFLV SEYLKDASKKMKNGLMFVKL VNPCSGEGAIYLFNMCLQQL FEVKVFKEKHHSWFINQSVQ SGGLLHFATPVDPLFLLLHY LIKADKEGKFQPLDQVVVDN VFPNCILLLKLPGLEKLLHH VTEEKGNPEIDNKKYYKYSK EKTLKWLEKKVNQTVAALKT NNVNVSSRVQSTAFFSGDQA STDKEEDYIRYAHGLISDYI PKELSDDLSKYLKLPEPSA |
| Tissue Specificity | Widely expressed. |
| Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
| Protein Name | Ribonuclease H2 Subunit BRnase H2 Subunit BAicardi-Goutieres Syndrome 2 ProteinAgs2Deleted In Lymphocytic Leukemia 8Ribonuclease Hi Subunit B |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Ribonuclease H2 Subunit B antibodyAnti-Rnase H2 Subunit B antibodyAnti-Aicardi-Goutieres Syndrome 2 Protein antibodyAnti-Ags2 antibodyAnti-Deleted In Lymphocytic Leukemia 8 antibodyAnti-Ribonuclease Hi Subunit B antibodyAnti-RNASEH2B antibodyAnti-DLEU8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MSH6 knockout (KO) HeLa cells, using [KO Validated] MSH6 Rabbit polyclonal antibody (STJ119980) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98765/382817/STJ119980_1__09948.1713151312.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MSH6 knockout (KO) HeLa cells, using [KO Validated] MSH6 Rabbit polyclonal antibody (STJ119980) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")
