Function | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
Protein Name | Ribosomal Oxygenase 260s Ribosomal Protein L27a Histidine HydroxylaseBifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase MinaHistone Lysine Demethylase MinaMyc-Induced Nuclear AntigenMineral Dust-Induced Gene ProteinNucleolar Protein 52Ribosomal Oxygenase MinaRox |
Database Links | Reactome: R-HSA-3214842Reactome: R-HSA-9629569 |
Cellular Localisation | NucleusNucleolus |
Alternative Antibody Names | Anti-Ribosomal Oxygenase 2 antibodyAnti-60s Ribosomal Protein L27a Histidine Hydroxylase antibodyAnti-Bifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase Mina antibodyAnti-Histone Lysine Demethylase Mina antibodyAnti-Myc-Induced Nuclear Antigen antibodyAnti-Mineral Dust-Induced Gene Protein antibodyAnti-Nucleolar Protein 52 antibodyAnti-Ribosomal Oxygenase Mina antibodyAnti-Rox antibodyAnti-RIOX2 antibodyAnti-MDIG antibodyAnti-MINA antibodyAnti-MINA53 antibodyAnti-NO52 antibody |
Information sourced from Uniprot.org