• Western blot analysis of extracts of various cell lines, using RHBDL2 antibody (STJ116617) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 40s.

Anti-RHBDL2 antibody (12-130) (STJ116617)

SKU:
STJ116617

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RHBDL2 (12-130) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RHBDL2
Gene ID: 54933
Uniprot ID: RHBL2_HUMAN
Immunogen Region: 12-130
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 12-130 of human RHBDL2 (NP_060291.2).
Immunogen Sequence: MNLNMGREMKEELEEEEKMR EDGGGKDRAKSKKVHRIVSK WMLPEKSRGTYLERANCFPP PVFIISISLAELAVFIYYAV WKPQKQWITLDTGILESPFI YSPEKREEAWRFISYMLVH
Post Translational Modifications Proteolytic processing of the proenzyme produces a N-terminal fragment (NTF) and a C-terminal fragment (CTF). The processing is required for activation of the protease.
Function Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Known substrate: EFNB3.
Protein Name Rhomboid-Related Protein 2
Rrp2
Rhomboid-Like Protein 2 Cleaved Into - Rhomboid-Related Protein 2 - N-Terminal Fragment
Ntf - Rhomboid-Related Protein 2 - C-Terminal Fragment
Ctf
Cellular Localisation Rhomboid-Related Protein 2
C-Terminal Fragment: Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Rhomboid-Related Protein 2 antibody
Anti-Rrp2 antibody
Anti-Rhomboid-Like Protein 2 Cleaved Into - Rhomboid-Related Protein 2 - N-Terminal Fragment antibody
Anti-Ntf - Rhomboid-Related Protein 2 - C-Terminal Fragment antibody
Anti-Ctf antibody
Anti-RHBDL2 antibody

Information sourced from Uniprot.org

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