• Western blot analysis of various lysates using RGMB Rabbit polyclonal antibody (STJ114725) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-RGMB antibody (210-453) (STJ114725)

SKU:
STJ114725

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-RGMB (210-453) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: RGMB
Gene ID: 285704
Uniprot ID: RGMB_HUMAN
Immunogen Region: 210-453
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 210-453 of human RGMB (NP_001012779.2).
Immunogen Sequence: PHLRTFKDNFQTCKVEGAWP LIDNNYLSVQVTNVPVVPGS SATATNKITIIFKAHHECTD QKVYQAVTDDLPAAFVDGTT SGGDSDAKSLRIVERESGHY VEMHARYIGTTVFVRQVGRY LTLAIRMPEDLAMSYEESQD LQLCVNGCPLSERIDDGQGQ VSAILGHSLPRTSLVQAWPG YTLETANTQCHEKMPVKDIY FQSCVFDLLTTGDANFTAAA HSALEDVEALHPRKERWHI
Post Translational Modifications GPI-anchored. Autocatalytically cleaved at low pH.the two chains remain linked via two disulfide bonds.
Function Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling. Promotes neuronal adhesion. May inhibit neurite outgrowth.
Protein Name Repulsive Guidance Molecule B
Drg11-Responsive Axonal Guidance And Outgrowth Of Neurite
Dragon
Database Links Reactome: R-HSA-373752
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Membrane Raft
Alternative Antibody Names Anti-Repulsive Guidance Molecule B antibody
Anti-Drg11-Responsive Axonal Guidance And Outgrowth Of Neurite antibody
Anti-Dragon antibody
Anti-RGMB antibody

Information sourced from Uniprot.org

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