| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RFTN2 (412-501) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RFTN2 |
| Gene ID: |
130132 |
| Uniprot ID: |
RFTN2_HUMAN |
| Immunogen Region: |
412-501 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 412-501 of human RFTN2 (NP_653230.2). |
| Immunogen Sequence: |
KKASRHIKGEDKNKATSRSI GLDTTSSQPAESRHLPEECR LSPSRECWTKEGRLAQHNSF SGFSSSDNVLRELDDGQFDQ EDGVTQVTCM |
| Function | Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling. |
| Protein Name | Raftlin-2Raft-Linking Protein 2 |
| Cellular Localisation | Cell MembraneLipid-Anchor |
| Alternative Antibody Names | Anti-Raftlin-2 antibodyAnti-Raft-Linking Protein 2 antibodyAnti-RFTN2 antibodyAnti-C2orf11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
