| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RECQL4 |
| Gene ID: |
9401 |
| Uniprot ID: |
RECQ4_HUMAN |
| Immunogen Region: |
231-330 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 231-330 of human RECQL4 (NP_004251.3). |
| Immunogen Sequence: |
GAGSQGPEASAFQEVSIRVG SPQPSSSGGEKRRWNEEPWE SPAQVQQESSQAGPPSEGAG AVAVEEDPPGEPVQAQPPQP CSSPSNPRYHGLSPSSQARA |
| Tissue Specificity | Ubiquitously expressed, with highest levels in thymus and testis. |
| Function | An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction. Does not unwind more than 18 bp of dsDNA. May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA. The core helicase domain binds ssDNA. |
| Protein Name | Atp-Dependent Dna Helicase Q4Dna 3'-5' Helicase Recq4Dna Helicase - Recq-Like Type 4Recq4RtsRecq Protein-Like 4 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Atp-Dependent Dna Helicase Q4 antibodyAnti-Dna 3'-5' Helicase Recq4 antibodyAnti-Dna Helicase - Recq-Like Type 4 antibodyAnti-Recq4 antibodyAnti-Rts antibodyAnti-Recq Protein-Like 4 antibodyAnti-RECQL4 antibodyAnti-RECQ4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from A549 cells using [KD Validated]Smad6 Rabbit polyclonal antibody (STJ11105286) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/177930/369944/STJ11105286_1__46686.1713135852.jpg?c=1 "Western blot analysis of lysates from A549 cells using [KD Validated]Smad6 Rabbit polyclonal antibody (STJ11105286) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.")
