| Host: | Rabbit |
| Applications: | IF/IHC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-Recombinant-Polypyrimidine Tract-Binding Protein 2 is suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot research applications. |
| Clonality : | Monoclonal |
| Clone ID : | RM1A34 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.01M PBS, pH 7.4, 0.05% BSA, 50% Glycerol, 0.05% Sodium azide |
| Purification: | Protein A/G purified from cell culture supernatant |
| Dilution Range: | IF: 1:50-1:200, IHC: 1:100-1:200, WB: 1:1000-1:2000 |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | PTBP2 |
| Gene ID: | 58155 |
| Uniprot ID: | PTBP2_HUMAN |
| Function | RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5: Reduced affinity for RNA. |
| Protein Name | Polypyrimidine Tract-Binding Protein 2Neural Polypyrimidine Tract-Binding ProteinNeurally-Enriched Homolog Of PtbPtb-Like Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Polypyrimidine Tract-Binding Protein 2 antibodyAnti-Neural Polypyrimidine Tract-Binding Protein antibodyAnti-Neurally-Enriched Homolog Of Ptb antibodyAnti-Ptb-Like Protein antibodyAnti-PTBP2 antibodyAnti-NPTB antibodyAnti-PTB antibodyAnti-PTBLP antibody |
Information sourced from Uniprot.org