Host: | Rabbit |
Applications: | FC/IF/IP/WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit monoclonal antibody anti-Recombinant-Malate Dehydrogenase-Cytoplasmic is suitable for use in Flow Cytometry, Immunofluorescence, Immunoprecipitation and Western Blot research applications. |
Clonality : | Monoclonal |
Clone ID : | RM1V77 |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.01M PBS |
Purification: | Protein A/G purified from cell culture supernatant |
Dilution Range: | FCM: 1:20-1:100 |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Gene Symbol: | MDH1 |
Gene ID: | 4190 |
Uniprot ID: | MDHC_HUMAN |
Function | Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS). |
Protein Name | Malate Dehydrogenase - CytoplasmicAromatic Alpha-Keto Acid ReductaseKarCytosolic Malate Dehydrogenase |
Database Links | Reactome: R-HSA-9856872 |
Cellular Localisation | CytoplasmCytosol |
Alternative Antibody Names | Anti-Malate Dehydrogenase - Cytoplasmic antibodyAnti-Aromatic Alpha-Keto Acid Reductase antibodyAnti-Kar antibodyAnti-Cytosolic Malate Dehydrogenase antibodyAnti-MDH1 antibodyAnti-MDHA antibody |
Information sourced from Uniprot.org