Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1-like and core 2-like glycans. O-glycan heterogeneity at Ser-53: HexHexNAc (major) and Hex2HexNAc2 (minor). N-glycan heterogeneity at Asn-103: Hex5HexNAc4 (minor), dHex1Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).N-glycan at Asn-147: dHex1Hex5HexNAc4. |
Function | Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. |
Protein Name | Interleukin-18-Binding ProteinIl-18bpTadekinig-Alfa |
Database Links | Reactome: R-HSA-9008059Reactome: R-HSA-9012546 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Interleukin-18-Binding Protein antibodyAnti-Il-18bp antibodyAnti-Tadekinig-Alfa antibodyAnti-IL18BP antibody |
Information sourced from Uniprot.org