Anti-Recombinant-DRD3/Dopamine D3 receptor antibody [RM1V04] (STJA0024483)

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STJA0024483
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal antibody anti-Recombinant-D (3 Dopamine Receptor is suitable for use in Western Blot research applications.
Clonality : Monoclonal
Clone ID : RM1V04
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Dilution Range: WB: 1:1000-1:2000
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: DRD3
Gene ID: 1814
Uniprot ID: DRD3_HUMAN
Post Translational Modifications Phosphorylated by GRK4 (GRK4-alpha and GRK4-gamma). Palmitoylated.
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
Protein Name D(3 Dopamine Receptor
Dopamine D3 Receptor
Database Links Reactome: R-HSA-390651
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Both Membrane-Bound And Scattered In The Cytoplasm During Basal Conditions
Receptor Stimulation Results In The Rapid Internalization And Sequestration Of The Receptors At The Perinuclear Area (5 And 15 Minutes)
Followed By The Dispersal Of The Receptors To The Membrane (30 Minutes)
Drd3 And Grk4 Co-Localize In Lipid Rafts Of Renal Proximal Tubule Cells
Alternative Antibody Names Anti-D(3 Dopamine Receptor antibody
Anti-Dopamine D3 Receptor antibody
Anti-DRD3 antibody

Information sourced from Uniprot.org

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